Journal: Balkan Medical Journal
Article Title: Fucoxanthin Attenuates Bisphenol A-Induced Testicular Injury via NF-κB-Mediated Pyroptosis Inhibition
doi: 10.4274/balkanmedj.galenos.2026.2025-11-268
Figure Lengend Snippet: Effects of Fx on the pyroptosis signaling pathway in vitro . (a, b) The mRNA levels of Casp1 and Gsdmd ; (c) Western blotting analysis of the expression of Caspase-1, Caspase-1 p20, GSDMD, and N-GSDMD; (d-f) the quantification of the Western blotting analysis; (g, h) IL-1β and IL-18 concentrations in TM3 cell supernatant. Data presentation and statistical analysis are as described for Figure 1 (n = 3). * p < 0.05, ** p < 0.01, *** p < 0.001. BPA, bisphenol A; Fx, fucoxanthin; GSDMD, gasdermin D; IL-1β, interleukin-1β; IL-18, interleukin-18.
Article Snippet: The TM3 Leydig cell line (CL0234), TM3 Cell Complete Medium (CM-0234), and DMEM/F12 (PM150312) were provided by Procell Life Science & Technology (Wuhan, China).
Techniques: In Vitro, Western Blot, Expressing